Content

At increased activity in the body of fungi of the genus Candida albicans, doctors recommend medicinal product Pimafucin (Pimafucin). This medicine has three dosage forms, characterized by local action in the body. Self-medication is contraindicated.

Composition

The drug Pimufacin is a representative of the pharmacological group of antimycotic agents. A drug with fungicidal and antifungal properties is produced in the form of vaginal suppositories, tablets and cream. Features of each release form:

  1. Round white tablets are enteric-coated. The medicine is packaged in glass bottles of 20 pcs. Instructions for use are included in the carton box.
  2. Light yellow torpedo-shaped suppositories are intended for intravaginal use. The drug is packaged on aluminum foil scripts, 3 pcs. The carton contains 2-3 scripts and annotation.
  3. Light cream-colored cream with a specific odor is intended for local use (externally). The medicinal composition is poured into aluminum tubes, 30 g each.

Features of the chemical composition of Pimafucin depend on the form of release, are described in detail in the instructions. The active substance is the same, called natamycin. The concentration in tablets, suppositories and cream is different:

Release form

Active ingredient, g

Excipients

Shell composition

pills

natamycin (0.1)

povidone K30, lactose monohydrate, potato starch, magnesium stearate

methyl parahydroxybenzoate, sucrose, titanium dioxide, gelatin, kaolin, talc, white beeswax, acacia gum, calcium carbonate, triacetin, cellacephate

natamycin (0.2)

decyloleate, cetyl ether wax, methyl parahydroxybenzoate, propylene glycol, purified water, cetostearyl alcohol, sodium lauryl sulfate, propyl parahydroxybenzoate.

vaginal suppositories

natamycin (0.1)

solid fat, polysorbate 80, sodium bicarbonate, sorbitan trioleate, cetyl alcohol, adipic acid

Pharmacodynamics and pharmacokinetics

Detailed instructions for the use of Pimufacin report that natamycin, being a polyene (tetraene) antibiotic of the macrolide group, binds to the walls of a pathogenic fungus, violates their integrity, and inhibits further growth and spread of pathogenic flora. Pimafucin is active against yeast and molds. Positive dynamics is observed with activity:

  • Candida
  • Aspergillus;
  • Cephalosporium;
  • Fusarium;
  • Penicillium.

When using this medication against Pseudoallescheria boydii and dermatophytes, a mediocre therapeutic effect is observed, so it is better to immediately select an analogue. Pimafucin is absorbed in the lumen of the large intestine, the active substance in relatively small doses enters the bloodstream. With a local area of ​​​​application of the drug, a mediocre effect on the focus of pathology is observed.

Indications for use

  • cream: ringworm, diaper rash, vulvovaginitis, vulvitis, vaginitis, otitis media, candidiasis of the nail plates and skin;
  • tablets: candidiasis of the intestinal mucosa, long-term antibiotic therapy, taking cytostatics, corticosteroids, acute atrophic candidiasis, acute pseudomembranous candidiasis with cachexia;
  • vaginal suppositories: thrush, vulvovaginal candidiasis, vulvovaginitis, vulvitis, balanoposthitis.

Method of application and dosage

The drug Pimafucin productively destroys pathogenic fungi of different localization in the body. The recommended daily doses and method of application of the drug depend on the form of release and the nature of the pathological process. Before starting the course, you should individually consult with your doctor.

Candles Pimafucin

The drug Pimafucin from thrush is more often recommended in the form of vaginal suppositories. The patient is required to insert 1 suppository through the vagina for 5-7 days without interruption. In a complicated clinical case, the course of treatment is extended to 2-3 weeks. It is advisable to carry out the home procedure before going to bed, or after the introduction of the suppository, remain in a horizontal position for some time. Otherwise, the therapeutic composition flows out and the desired therapeutic effect is weakened. Candles are not prescribed for men.

Cream

This form of release of Pimafucin is equally suitable for women and men in the complex treatment of balanoposthitis, vulvovaginitis and vulvitis. The drug is intended for external use. According to the instructions, it is required to apply the therapeutic composition to the foci of pathology (skin, nails, genitals) up to 3-4 times a day. The course of treatment depends on the stage of the pathological process, negotiated individually.

Pimafucin tablets

With progressive intestinal candidiasis, doctors recommend taking Pimafucin tablets for a weekly course. During this time, an adult patient takes 4 tablets, a child - 2 tablets. per day. The recommended dose of the drug should be swallowed whole with water. Do not pre-chew or dissolve in the oral cavity.

Pimafucin for men

With an exacerbation of candidiasis, doctors prescribe topical application of Pimafucin cream to men. In complicated clinical cases, an integrated approach to the health problem is recommended. Topical application of the cream is supplemented by oral administration of tablets. Daily doses and course of treatment with Pimafucin depend on the disease, negotiated individually with a specialist.

special instructions

Treatment of thrush with Pimafucin takes place in full, even if positive changes in well-being are noticeable after 2-3 days. If prematurely terminated drug therapy, the disease progresses again. Instructions for use contains instructions for patients:

  1. Pimafucin is prescribed with caution for glucose-galactose malabsorption, lactase deficiency.
  2. children infancy tablets are not prescribed, since there are difficulties with their oral administration.
  3. The drug does not depress functions nervous system therefore, during treatment it is allowed to drive a vehicle, engage in intellectual activities.

During pregnancy

Pimafucin is recommended for use by pregnant women. Treatment proceeds under medical supervision with individual correction of the prescribed daily dosages. In chronic infections, oral tablets are often supplemented with topical use of vaginal suppositories. The course of treatment lasts from 7 to 10 days. With lactation, such a pharmaceutical appointment is also not prohibited. Doctors recommend temporarily stopping breast-feeding, transfer the child to adapted mixtures.

Pimafucin for children

With organ candidiasis gastrointestinal tract doctors do not prohibit the use of Pimafucin in childhood. According to the instructions for use, the recommended dosage is 1 tab. in the morning and in the evening. In complicated clinical cases, the allowable dose is increased to 4 pcs. Additional use of suppositories and Pimafucin cream is negotiated with the pediatrician.

drug interaction

Tablets, cream and suppositories from thrush Pimafucin are recommended to the patient in the composition complex treatment for the extermination of pathogenic flora of a fungal nature. AT detailed instructions on the application of information about drug interaction with representatives of other pharmacological groups not provided. Doctors warn patients against self-medication.

Side effects

Pimafucin is characterized by good tolerance by the affected organism. Side effects occur extremely rarely, are presented in the instructions for use of the drug:

  • digestive tract: nausea, vomiting, diarrhea;
  • allergic reactions: skin rash, urticaria, swelling and hyperemia of the epidermis;
  • local reactions when using suppositories and cream.

Contraindications

The drug Pimafucin is not approved for use by all patients. According to the instructions, the list of medical contraindications is limited to the increased sensitivity of the body to the active ingredients of the specified antifungal agent. Age restrictions are required to be individually coordinated with a dermatologist, a local pediatrician.

Terms of sale and storage

Pimafucin is sold in a pharmacy, released without a prescription. According to the instructions for use, it is required to store the medication in a dry and cool place, away from sunlight, inaccessible to small children. The shelf life of Pimafucin is 24 months.

Analogues

If Pimafucin does not help to exterminate the pathogenic flora, doctors recommend replacing the antifungal drug. Reliable medicines with antimycotic and fungicidal action, their brief characteristics:

  1. Alpha Normix. These are round orange tablets with rifaximin in chemical composition. According to the instructions, the patient is prescribed 1 table. every 8 hours. The course of treatment is no longer than 7 days, the doses are adjusted individually.
  2. Nystatin-Health. An antifungal agent in the form of film-coated tablets containing nystatin in the chemical composition. According to the instructions, appoint 1-2 tablets. per day for 1-2 weeks without a break.
  3. Nystatin. These are vaginal suppositories, ointment and capsules with the same active ingredient. According to the instructions, these forms of release are allowed to be combined in one treatment regimen to enhance the therapeutic effect.
  4. Livarol. These are vaginal suppositories recommended for thrush, with ketoconazole in the chemical composition. According to the instructions for use, the drug is allowed during pregnancy and lactation. The patient is prescribed 1-2 soup. per day.
  5. Terzhinan. This is an expensive drug with an antifungal effect in the form of vaginal suppositories. According to the instructions, the patient is prescribed 1 suppository at bedtime. After the dose is administered, it is recommended not to get out of bed.
  6. Clotrimazole. This medication has five forms of release - gel, cream, ointment, solution, tablets, vaginal suppositories. Contains the component of the same name of different concentration. Daily doses and course of treatment are described in the instructions for use.

Pimafucin price

The cost of this medication varies from 450 to 600 rubles. Buying online is cheaper for the patient. The retail price depends on the form of release of the drug, the configuration of each package, the rating of the capital's pharmacy.

Video

Pimafucin is a drug with fungicidal (antifungal) action.

Release form and composition

Pimafucin is available in three dosage forms:

  • Enteric-coated tablets: round, white (20 pieces in dark glass bottles, 1 bottle in a carton box);
  • Vaginal suppositories: from light yellow with a brown tint to white with a yellow tint, torpedo-shaped (3 pcs in aluminum foil strips, 1 or 2 strips in a cardboard box);
  • Cream for external use 2%: from light yellow to white (30 g each in aluminum or plastic tubes, 1 tube in a cardboard box).

The composition of 1 tablet includes:

  • Auxiliary components and shell: cellacephate - 18 mg, potato starch - 79.2 mg, povidone K30 - 5 mg, magnesium stearate - 2.5 mg, methyl parahydroxybenzoate - 0.07 mg, lactose monohydrate - 66 mg, triacetin - 2.7 mg, sucrose - 122 mg, calcium carbonate - 30 mg, kaolin - 14.2 mg, titanium dioxide - 3 mg, talc - 21.7 mg, acacia gum - 7.3 mg, gelatin - 3.3 mg, white bee wax - 0.13 mg.

The composition of 1 suppository includes:

  • Active ingredient: natamycin - 100 mg;
  • Auxiliary components: polysorbate 80 - 460 mg, cetyl alcohol - 690 mg, sorbitan trioleate - 460 mg, solid fat - 700 mg, sodium bicarbonate - 69 mg, adipic acid - 64 mg.

The composition of 100 mg of cream includes:

  • Active ingredient: natamycin - 2 mg
  • Auxiliary components: cetyl ether wax - 5 mg, decyloleate (cetiol V) - 10 mg, sodium lauryl sulfate - 1.5 mg, propylene glycol - 15 mg, propyl parahydroxybenzoate - 0.1 mg, methyl parahydroxybenzoate - 0.2 mg, cetostearyl alcohol - 13, 5 mg, purified water - up to 100 mg.

Indications for use

Pills

  • intestinal candidiasis;
  • Acute pseudomembranous and atrophic candidiasis in patients with immune deficiency, cachexia, as well as after the use of antibiotics, corticosteroids and cytostatics;
  • Sanitation of the intestinal reservoir of fungi of the genus Candida in candidiasis of the skin and mucous membranes, including candidal vaginitis, vulvovaginitis and vulvitis.

Vaginal suppositories

  • Vulvitis, vaginitis, vulvovaginitis, caused mainly by fungi of the genus Candida.

External cream
Fungal diseases of the skin and mucous membranes caused by pathogens sensitive to the action of the active substance, including diseases such as:

  • Balanoposthitis, vulvovaginitis, vulvitis, caused mainly by fungi of the genus Candida;
  • Otitis externa (complicated by candidiasis or primarily caused by fungi);
  • Candidiasis of nails and skin;
  • Dermatomycosis.

Contraindications

The use of Pimafucin in any dosage form is contraindicated in the presence of hypersensitivity to the components of the drug.

Method of application and dosage

The doctor sets the duration of the treatment course individually. After the disappearance of the symptoms of the disease, it is recommended to continue treatment for a few more days.

Pills
Pimafucin is taken orally, regardless of the meal.

A single dose for intestinal candidiasis is 1 tablet. The recommended frequency of taking the drug: adults - 4 times a day, children - 2 times a day. The average duration of the treatment course is 7 days.

With a persistent course of vaginitis associated with fungi of the genus Candida, for the sanitation of the focus of candidal infection in the intestine, 1 tablet is prescribed 4 times a day simultaneously with the use of local antifungal drugs (for example, with Pimafucin in the form of suppositories). The average duration of the treatment course is 10-20 days.

Vaginal suppositories
Pimafucin is used intravaginally, introducing the suppository as deep as possible in the supine position with bent legs.

With persistent vaginitis associated with Candida albicans, vaginal suppository therapy is usually combined with taking Pimafucin in the form of tablets.

In the treatment of candidal lesions of the genital organs of a partner, the drug is used in the form of a cream.

External cream
Pimafucin is applied to the affected surface of the skin.

  • Dermatomycosis (including skin candidiasis, diaper rash in children): 1-4 times a day;
  • Mycosis of the external auditory canal: 1-4 times a day. The ear should be cleaned before application. After applying Pimafucin, it is necessary to place a swab made of natural material (cotton wool, gauze) into the ear canal;
  • Vulvitis, vulvovaginitis, balanoposthitis: 1-2 times a day.

Side effects

In case of aggravation of any of the described side effects or with the development of undesirable effects not indicated in the instructions, it is necessary to consult a specialist.

Pills
In the first days of admission, there may be disturbances in the gastrointestinal tract in the form of nausea and diarrhea. As a rule, these side effects pass independently and do not require additional therapy.

Vaginal suppositories, external cream
During the use of Pimafucin, local reactions may develop in the form of mild irritation and a burning sensation.

special instructions

Pills
In the presence of rare congenital fructose / galactose intolerance, lactase deficiency, glucose-galactose malabsorption or sucrose-isomaltase deficiency, it should be borne in mind that Pimafucin contains lactose monohydrate and sucrose (before starting therapy, consultation with a specialist is necessary).

It is not recommended to use Pimafucin in the form of tablets for infants (due to difficulty in swallowing).

Vaginal suppositories
Under the influence of body temperature, suppositories quickly dissolve with the formation of a foamy mass, due to which the active substance is evenly distributed along the walls of the vagina.

Local therapy for recurrent or chronic infection can be supplemented with other dosage forms of Pimafucin.

Cetyl alcohol in the presence of hypersensitivity to it can cause a slight burning sensation.

At the time of menstruation, treatment should be interrupted.

During the period of therapy, there is no need to exclude sexual intercourse. However, if a candidal lesion is detected, examination of both sexual partners is recommended.

During treatment, it is necessary to use barrier contraceptives.

External cream
With recurrent or chronic infections, local therapy can be supplemented by taking Pimafucin inside.

The cream can be used in newborns.

drug interaction

The interaction of Pimafucin with other drugs / substances has not been found.

Terms and conditions of storage

Keep out of the reach of children at temperatures up to 25 °C.

Shelf life:

  • Tablets, cream - 4 years;
  • Suppositories - 2 years.

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An effective pharmacological agent with a pronounced antifungal activity is an antibiotic from the pimafucin macrolide subgroup. What does the medicine help? The drug has a predominantly fungicidal effect. It has proven itself in the practice of dermatological specialists. Tablets, cream, suppositories "Pimafucin" instructions for use suggest using for thrush, ringworm, balanoposthitis, otitis media of fungal etiology.

Available release forms

The medicine is currently available in three main forms - not only tablets, but also cream, as well as vaginal suppositories.

Rounded with whitish staining tablets are packaged in dark glass bottles - 20 pcs. The form of the cream has a whitish or yellowish color, is packed in 30 g each in special tubes made of aluminum or medical plastic. The form of suppositories "Pimafucin" (candles), which helps with vulvovaginitis, is sold in special foil strips. In consumer packaging, 3 pcs. Packing for 1 or 2 strips.

Active and auxiliary components

The manufacturer in the instructions for the drug "Pimafucin" indicates Natomycin as the active substance. It is he who has fungicidal effects. Of the excipients are listed - cetyl alcohol, adapic acid, as well as hard fat and polysorbate 80, and sorbitan trioleate, and sodium bicarbonate.

The main substance of the ointment form of the drug is Natamycin. Designed for outdoor use. The auxiliary components are listed in the instructions as follows - propylene glycol and cetostaeric alcohol, sodium lauripsulfate and purified, as well as decyloleate and methyl parahydroxybenzoate, there are also cetyl wax ester and propyl parahydroxybenzoate.

The pharmacy form of the tablets contains the active substance Natamycin, and the auxiliary components are: kaolin and white beeswax, as well as polyvinylpyrrolidone. It is in the complex that they provide a pronounced fungicidal effect.

Pharmacological properties

Specialists of the pharmacological agent "Pimafucin", instructions for use inform about this, attributed to polyene antibiotics of the macrolide subgroup with pronounced antifungal activity. It has a wide range of effects, the fungicidal effect is especially pronounced. The active substance - Natamycin, binds the sterols of the membranes of the cells of the fungal flora, thereby violating its overall integrity, and also contributing to the failure functionality. Ultimately, the death of the fungus is observed.

Many pathogenic yeast fungi, for example, the genus Candida albicans, are susceptible to Natamycin. not as sensitive to active substance medication "Pimafucin" dermatophytes. At the same time, absolute resistance to the drug is not observed at all.

With the oral route of administration of the drug, Natamycin is practically not absorbed from the structures of the gastrointestinal tract. When used externally - distribution over tissues, minimally absorbed. That is why the systemic effect is not observed.

Tablets, ointment, suppositories "Pimafucin": what helps the medicine

With diagnosed fungal infections of the nail tissues, or skin, as well as mucous membranes, specialists recommend course therapy with the Pimafucin medication. The instruction reveals the main indications when the medicine helps:

  • candidiasis of nails, dermis;
  • dermatomycosis;
  • various vulvitis;
  • balanoposthitis;
  • otitis media provoked by fungal flora;
  • vulvovaginitis.

In the form of tablets, the remedy is very effective for fungal pathologies of the ear canal, in its outer part, as well as the mucous tissues of the oral cavity. The agent can be recommended when diagnosing candidiasis of intestinal loops, as well as after therapy with various cortecosteroids, drugs from antibacterial subgroups, and cytostatics.

What helps candles "Pimafutsin"? Suppositories are recommended in the complex therapy of thrush, balanoposthitis and vulvovaginitis, as well as vulvitis and viginitis, provoked by the fungal flora of the genus Candida.

Unwanted Effects

Of the contraindications, the instructions for the pharmacological agent indicate only human intolerance to the active and auxiliary components of the Pimafucin medication, from which suppositories and other forms can cause body reactions.

In most cases, the medication is well tolerated by patients. The following negative effects occur less frequently:

  • dyspeptic manifestations - nausea;
  • diarrhea - on the first day of oral administration of the medication, it is eliminated on its own;
  • mild irritation;
  • discomfort and burning sensation - with the introduction of a form of cream, suppositories.

The drug "Pimafucin": instructions for use

In the instructions for use attached to each package with one or another form of the Pimafucin medication, it is prescribed in detail how the medicine should be used:

  1. Suppositories are intended for intravaginal administration - with diagnosed vulvovaginitis and vulvitis, or vaginitis: 1 pc. For 3-6 days. Enter carefully, better lying down, before a night's rest, deeply. If the therapy of vaginitis only with suppositories is ineffective, then a course of taking tablets is recommended - 1 pc. four times a day, 10-15 days. The duration of treatment is determined by the specialist individually, in direct proportion to the severity of the identified pathology. After the disappearance of the main clinical manifestations it is recommended to continue the procedure for another 3-5 days in order to prevent relapse.
  2. Medicinal cream "Pimafucin" for external use - the affected areas of the body are applied 1-3 times a day: with balanoposthitis or vulvovaginitis. If the negative symptoms are not eliminated, it is recommended to use the form of suppositories or tablets. With confirmed ringworm, including fungal diaper rash in babies and candidiasis of the nail plates, the suspension is applied up to 3-4 times a day.
  3. With fungal mycosis of the external passage of the auricle, the affected area is washed off with a medicinal cream 3-4 times a day, with preliminary thorough cleaning of the ear. After applying the medication, a turunda is inserted into the ear. The duration of such therapy is determined by the specialist individually. After relief of the main symptoms, it is recommended to continue the procedure for another 2-3 days.

Tablets "Pimafucin" - with candidiasis of intestinal loops, 1 pc. 4 times a day, in pediatric practice, 1 pc. 2 r / s. The average duration of treatment is 5-7 days.

Analogues of the drug "Pimafucin"

The same active element in its composition contains analogues:

  1. "Natamycin".
  2. "Primafungin".
  3. Ecofucin.

Price

Vaginal suppositories "Pimafutsin" in Moscow and other regions of Russia can be bought for 278 rubles. This is the price of 3 suppositories. For 20 tablets, you will have to pay 458, for a cream - 320 rubles. In Ukraine, the medicine is sold for 85-176 hryvnias. In Minsk, the drug costs 10-29 Belarusian rubles. rubles. You can buy a tube of ointment 30 g in Kazakhstan for 2000 tenge.

Pimafucin is an antifungal drug that is part of the macrolide group and has a fungicidal effect.

The active substance of the drug is natamycin. The drug is used for various fungal diseases of the skin, nails, vulvovaginal candidiasis, fungal diseases of the gastrointestinal tract. The drug can be used during pregnancy.

In this article, we will consider why doctors prescribe Pimafucin, including instructions for use, analogues and prices for this medicine in pharmacies. If you have already used Pimafucin, leave your feedback in the comments.

Composition and form of release

Clinico-pharmacological group: antifungal antibiotic.

  1. 1 tablet of Pimafucin contains 100 mg active substance and auxiliary components (potato starch, magnesium stearate, PVP, lactose, gelatin, calcium carbonate, kaolin, talc, triacetin, cellulose acetate phthalate, beeswax, titanium oxide, sucrose). Pimafucin tablets are produced in an enteric coating, in bottles of 20 tablets, along with instructions for use.
  2. IN 1 vaginal suppositories contains 100 mg of natamycin, as well as auxiliary components (cetyl alcohol, solid fat, polysorbate, sorbitol, sodium bicarbonate, adipic acid). Pimafucin suppositories are produced in a non-cell contour package of 3 suppositories. In a cardboard box 1 or 2 packs.
  3. Pimafucin cream is intended for external use. 1 g of cream contains 20 mg of natamycin, as well as auxiliary components (decyloleate, cetostearyl alcohol, wax, sodium lauryl sulfate, propylene glycol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, water). The cream is produced in tubes of 30 g, in a carton box 1 tube with instructions for use.

What is Pimafucin used for?

For cream - fungal diseases mucous membranes and skin caused by pathogens sensitive to natamycin, including:

  1. Candidiasis of the skin and nails;
  2. Dermatomycosis;
  3. Otitis externa caused by fungi or complicated by candidiasis;
  4. Vulvitis, vaginitis, balanoposthitis, vulvovaginitis caused by Candida.

For suppositories- fungal diseases of the mucous membranes of the genital organs, caused mainly by fungi of the genus Candida:

  1. vulvitis;
  2. vaginitis;
  3. Vulvovaginitis.

For tablets:

  1. intestinal candidiasis;
  2. Candidiasis of the skin and mucous membranes (including vulvitis, candidal vaginitis and vulvovaginitis) - for the sanitation of the intestinal reservoir of fungi of the genus Candida.
  3. Acute atrophic and acute pseudomembranous candidiasis with immune deficiency or cachexia, as well as after therapy with cytostatics, antibiotics or corticosteroids;

pharmachologic effect

Antifungal polyene antibiotic of the macrolide group with a wide spectrum of action. The drug is active against yeast (Torulopsis, Rhoduturola), yeast-like fungi (Candida albicans), dermatomycetes (Trichophyton, Microsporum, Epidermophyton), other pathogenic fungi (Aspergillus, Penicillium), and Trichomonas.

It has a fungicidal effect. Pimafucin binds sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms. Dermatophytes are less sensitive to natamycin, but resistance to natamycin does not occur in clinical practice. Not absorbed from the gastrointestinal tract, skin and mucous membranes.

Instructions for use

The drug is taken orally. Eating does not affect the effectiveness of the drug.

  • With a persistent course of vaginitis caused by fungi of the genus Candida, together with local antifungal drugs (for example, Pimafucin suppositories), Pimafucin tablets are used to sanitize the focus of candidal infection in the intestine (100 mg orally (1 tab.) 4 times / day for 10-20 days).
  • With intestinal candidiasis, adults are recommended to take 100 mg (1 tab.) 4 times / day, children - 100 mg (1 tab.) 2 times / day. The average duration of the course of treatment is 1 week.
  • Vaginal suppositories are prescribed for women with vulvitis, vulvovaginitis, vaginitis. The drug is administered as deeply as possible, in the supine position. The procedure is recommended to be done at bedtime for three to six days, using 1 candle per day. With a persistent course of candidal vaginitis, in addition to suppositories, Pimafucin tablets are prescribed, which are taken from 10 to 20 days. Dosage - 4 tablets daily at regular intervals.
  • Cream instructions. Applied externally. On the affected areas from one to several times a day, the ointment should be applied with balanoposthitis, vulvovaginitis and vulvitis. If the symptoms persist, suppositories or tablets are prescribed. With ringworm (including diaper rash in children and candidiasis of the nails and skin), the suspension should be applied to the nails and skin up to 4 times a day.

The duration of the course of treatment is set individually. After the disappearance of the symptoms of the disease, it is recommended to continue treatment for a few more days.

Contraindications

Pimafucin is contraindicated for use by persons who are hypersensitive to any ingredient of the drug. Patients suffering from galactose or fructose intolerance, glucose-galactose malabsorption, need to remember that the tablets contain lactose monohydrate and sucrose. All dosage forms of the drug are approved for use during pregnancy and breastfeeding.

Side effects

When using tablets: nausea and diarrhea (usually occur in the first days of treatment and disappear on their own with continued therapy). When applying the cream and suppositories: burning sensation, mild irritation.


Pregnancy and lactation

It is possible to use Pimafucin during pregnancy and lactation.

special instructions

Vaginal suppositories dissolve quickly under the influence of body temperature, forming a foamy mass, which contributes to a uniform distribution of the active substance.

In case of chronic or recurrent infection local treatment can be supplemented by the appointment of tablets and cream. Ethanol, which is part of vaginal suppositories, can cause hypersensitivity reactions. During menstruation, suppository therapy is interrupted.

During the period of treatment with suppositories, there is no need to exclude sexual intercourse. However, it is recommended to conduct an examination of sexual partners and, if a candidal lesion is detected, to conduct a course of treatment with Pimafucin. The use of barrier contraceptives during treatment should also be considered.

Analogues

  • Analogues of tablets: preparations Alfa Normix and Nystatin-Health.
  • Analogues in the form of suppositories: Nystatin, Livarol, Clotrimazole. The price of analogues of candles is from 37 to 320 rubles.

Pimafucin has an analogue cheaper - Nystatin, a domestic drug, similar in action.

Prices

The average price of PIMAFUCIN tablets in pharmacies (Moscow) is 400 rubles. Candles 260 rubles. Cream 250 rubles.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.