The immune system human body not always able to effectively eliminate viral and infectious manifestations. Therefore, it is very important to timely select an effective drug for the treatment of viral diseases. Candles Viferon for adults is effective remedy, which has a pronounced antimicrobial and antiviral effect.

Description of the medication

Before using any medication, you must familiarize yourself with its purpose, how the remedy should be used correctly, and to whom it is contraindicated.

Viferon is a powerful drug, the main purpose of which is to activate the immune system in the body, fight viruses and infections. This is a combined pharmacological agent and it contains recombinant alpha-interferon, as well as a complex of certain vitamins. Also in the composition there are auxiliary ingredients:

  • polysorbate;
  • tocopherol acetate;
  • vitamin C;
  • sodium ascorbate.

The main components can also include butter, cocoa and fat, which in the total composition do not exceed 1 gram. A medicine is produced in the form of suppositories, gel and ointment.

Description of suppositories:

  • candles in the form of a bullet, have a slightly pointed, oblong shape;
  • white color, slight yellowness is acceptable;
  • in a blister pack there are 5 or 10 suppositories.

The drug is released without a doctor's prescription. There are several types of Viferon candles, with a dosage of 150,000, 500,000, 1,000,000 and 3,000,000 IU, in which not only the dosage of the main components, but also the auxiliary ones, differ.

When buying a drug, be sure to pay attention to the dosage, since the number of times of use per day and the possibility of use for children and pregnant women depend on it.

Pharmacological properties

Many are interested in the question, why are Viferon suppositories prescribed and what are the main properties of the drug? It is worth noting that this modern facility, which contains the main component - alpha-interferon, contained in the human body. Candles with Viferon contribute to the activation of the protective functions of the human body, stimulate the immune system and fight various kinds of viruses.

In addition to the main component, ascorbic acid is present in the composition of the drug, which also has an antiviral effect and protects the body from harmful free radicals that cause most diseases.

Interesting fact:

Thanks to vitamin C, interferon activity increases, and tocopherol alpha helps to restore cells and relieve inflammation.

By prescribing Viferon for adults, the need for many antibiotics is eliminated, while the use of other drugs that are usually prescribed for viruses and infections is significantly reduced. It should not be noted that the duration of treatment is also significantly reduced. Having chosen such therapy, the organs of the gastrointestinal tract and other systems are affected with less intensity. The risk of occurrence and development of other diseases, characteristic after long-term therapy with various pills, is reduced.

It is worth noting that the drug helps to reduce the production of its own interferon, and does not improve immunity. In this regard, it is not recommended to use the drug too often and for a long time to avoid addiction. The dosage of Viferon suppositories for adults depends on the doctor's prescriptions and the degree of damage to the body by the virus. The instructions for the use of suppositories for adults Viferon have more detailed information about the composition, as well as the properties of the drug.

Video "The fight for immunity with Viferon"

An informative video with advice from a specialist who recommends using Viferon for immunostimulation.

Viferon for adults - indications

The main purpose of the remedy is the treatment of diseases of an infectious-viral nature. Diseases for which suppositories are used:

  • pathologies caused by infections of the urogenital system;
  • viral hepatitis;
  • sepsis, various infectious diseases, enteroviruses;
  • sharp respiratory diseases in adults and children;
  • cirrhosis of the liver;
  • complication of influenza and SARS;
  • intrauterine infections;
  • candidiasis;
  • cytomegalovirus;
  • chlamydial infections.

The drug is often prescribed to pregnant women and newborns, as the drug has a fairly safe composition.

Contraindications

It has been confirmed more than once that Viferon rectal suppositories are an absolutely safe pharmacological product, so they can be used by any category of patients.

However, even here there is a certain contraindication. This is an individual intolerance to any constituent component.

Suppositories are allowed to be used even during pregnancy and breastfeeding. However, in the first trimester, it is still worth refusing to use the remedy. This is due to the fact that the placenta has not yet fully formed, so all substances can penetrate to the fetus. Starting from the second trimester, Viferon is absolutely safe.

Do not use the product if you are allergic to the components. If you experience side effects and allergic reactions, you need to stop taking the drug and seek the advice of a doctor. Side effects may occur, most often they occur in the form of:

  • itching;
  • burning sensation;
  • rash.

Usually, after the abolition of suppositories, such symptoms disappear after 2-3 days.

Mode of application

Depending on the form of Viferon, the method of application of the drug also depends. Suppositories are administered rectally, into the rectum, several factors affect the daily dose, such as:

  • patient's age;
  • the nature of the virus and the disease itself;
  • features of the body (pregnancy, individual intolerance, etc.).

This pharmacological product is prescribed for the treatment of certain pathologies, while it can be used both as an independent remedy and in complex treatment.

For newborns and children up to 6 months

For premature babies, as well as children under the age of six months, daily dose is one suppository twice a day. It is necessary to choose a drug with a dosage of 150,000 IU. The duration of treatment depends on the stage and the disease itself, as well as on individual characteristics. It is determined by the doctor after the diagnosis.

For children aged 6 months to a year

Usually at this age, specialists prescribe this drug for the treatment of viral hepatitis C, D, B. 1 suppository in the anus, once a day. Dosage - 500 thousand IU. The course may vary.

Children under 12

To eliminate the symptoms of flu, colds, you must use one suppository, twice a day. The dosage of one candle is 150 thousand IU.

Dosage for adults

The number of suppositories administered, as well as their dose, depends primarily on the disease, stage and individual characteristics.

Chronic viral hepatitis is treated with suppositories with a dose of 3 million IU, one unit, twice a day. Usually the period of therapy is 10 days. After that, the attending physician should reduce the dosage, depending on whether the patient is on the mend.

Viferon suppositories - instructions for use in gynecology:

  • 500 thousand IU;
  • daily dose - 1 million IU, but at a time, in the evening.

The average length of the course is 5 days, after a five-day break the course is usually repeated.

Most often used to treat:

  • chlamydia;
  • candidiasis;
  • mycoplasmosis;
  • vaginosis and so on.

With genital herpes, suppositories are prescribed, while their dosage is 1 million IU, twice a day. For viral colds, suppositories of 500,000 IU are used, twice a day. The average course duration is a week. It is worth noting that the suppositories melt quickly, so it is better to store them in the refrigerator and remove them from individual packaging immediately before administration.

Use during pregnancy and lactation

During lactation, Viferon is prescribed to eliminate bacterial as well as infectious pathologies of various types. The dosage is the same as for adults. Up to 14 weeks, the use of suppositories is not recommended, due to insufficient research.

Overdose and adverse reactions

Another advantage of the drug is the fact that adverse reactions occur very rarely, since the drug has excellent tolerability.

If there side effects, then they are expressed locally - an allergy in the area anus, itching, burning, rash and discomfort. In this case, the doctor must assess the degree of allergy and draw a conclusion - leave suppositories for therapy or refuse to use them.

There are no data on overdose, however, as a result of non-compliance with the instructions, dangerous consequences are possible. Therefore, doctors and manufacturers recommend strictly adhering to the instructions and dosage.

Interaction with other drugs

It is worth being careful when combining Viferon suppositories with other drugs, since their main component can enhance the effect of such pharmacological products:

  • various kinds of antibiotics;
  • antiviral drugs of various forms;
  • antimicrobial agents;
  • immunostimulants.

Doctors note that constipation and stool disorders negatively affect the main effect of suppositories. Therefore, it is recommended to use laxatives or do an enema.

Viferon candles for men

Recently, quite often, many urologists prescribe Viferon suppositories to men, as they are excellent at fighting infections. But it is known that it is infections that become the main root causes of various male diseases starting with prostatitis.

That is why anti-infective drugs must be included in complex treatment. However, Viferon will not help get rid of male diseases on its own, so an appointment is necessary. additional drugs and treatments such as prostate massage, warm-ups, and more.

Viferon suppositories for prevention in adults

To date, the effect of the use of suppositories for prevention has already been confirmed. viral diseases as well as more serious pathologies. These include:

  • chlamydia;
  • cytomegalovirus;
  • toxoplasmosis in children and adults;
  • seasonal viral infections and diseases.

To prevent such infections and pathologies, it is necessary to use the drug according to the instructions, while using the smallest dosage. For help and recommendations, it is best to consult a doctor to prevent addiction.

Analogues

To date, the pharmacology market is developing well, so in pharmacies you can see many analogues of Viferon. These drugs are similar in composition, properties and indications. Analogues include:

  • Laferon;
  • Alfarekin;
  • Laferobion (no less effective and popular option);
  • Interferon and so on.

The exact analogue of Viferon has not yet been invented, however, the above medicines are very similar in composition. Their main component is identical.

How to store candles?

Like most other medicines, candles must be stored away from sunlight and heat appliances - fireplaces, batteries. The maximum allowable storage temperature is ten degrees. Therefore, the most suitable place for storage is the refrigerator.

You need to save the pharmacological product in the original packaging, without removing the suppositories from the blister in advance. The expiration date is 24 months from the date of production, it is strongly not recommended to use expired candles.

The immunomodulatory drug Viferon 1000000 helps to cure diseases that are difficult to treat. It allows you to suppress the reproduction of viruses and slow down the division of tumor cells. The drug is used to treat pathologies caused by fungal microorganisms and antibiotic-resistant bacteria. Viferon not only speeds up recovery, but also minimizes the risk of complications.

Other names and classification

International non-proprietary name

The World Health Organization has assigned the INN interferon alfa 2-b to the drug.

Trade names

Viferon, Fitomaks-Plus, Laferomaks.

Registration number

ATX

L03AB05 - interferon alfa-2b.

Composition and dosage forms

The active substance of Viferon is human recombinant interferon alfa-2b. Interferon is obtained by genetic engineering (without the use of donor blood).

The composition of the drug also includes antioxidants - alpha-tocopherol acetate (vitamin E) and ascorbic acid (vitamin C). Antioxidants slow down the breakdown of interferon molecules in the body. They increase the period of biological activity of the drug. As auxiliary additives, the preparation contains: disodium edetate dihydrate, polysorbate-80, cocoa butter, confectionery fat or cocoa butter substitute.

The drug is made in the form of rectal suppositories. Each suppository contains 1,000,000 IU of recombinant interferon alfa-2b.

Suppositories have a yellowish tint. Their color can be uniform or heterogeneous (marble or interspersed). Rectal suppositories resemble the shape of a bullet. On their cross section there is a recess resembling a funnel. Rectal suppositories provide a simple, safe and painless method of administration.

Pharmacological group

pharmachologic effect

Interferon alpha interacts with cells by binding to specific interferon receptors on their surface. It gets inside the cells and evaluates their genome. When foreign genes are detected, interferon stimulates the production of a transcriptional molecular complex that is capable of influencing the genes of the host cell. Under the influence of the complex, the genes responsible for the synthesis of proteins with antiviral action are activated.

Proteins created under the action of interferon destroy viral and cellular RNA without causing the death of the host cell.

The human cell remains alive, but loses the ability to support the reproduction of the virus. The "antiviral state" of the cell persists for 48-72 hours. After this period, its functions are restored. Interferon protects the genetic information of human cells, preventing viruses from changing it.

Recombinant interferon alpha blocks the reproduction of all types of human respiratory viruses. Because the drug has no direct effect on pathogens, pathogens cannot develop resistance to it. The drug is localized only in the affected area.

Interferon normalizes the level of immunoglobulin E (IgE) and has an immunomodulatory effect on T and B lymphocytes.

Therefore, it helps to treat diseases caused by bacteria and fungi. B cells recognize pathogens and form antibodies against them. T cells regulate the production of antibodies. The drug recognizes damaged and pathologically altered cells. It is able to reduce the malignancy of cancer cells (phenotypic reversion). Antioxidants increase the effectiveness of interferon by 10-14 times.

Viferon 1000000 allows you to quickly eliminate the symptoms of the disease (cough, pain, shortness of breath), reduce infectious intoxication and accelerate the elimination of the lesion. When the drug is included in the treatment regimen, recovery occurs 5-8 days earlier. Interferon helps reduce dosages hormonal drugs and antibiotics used to treat the disease. It reduces the toxic effects of drugs on the body.

Indications for use Viferon 1000000

Viferon is used to treat pathologies of a viral nature. It is prescribed to people who have an acute respiratory viral infection of the upper respiratory tract. The medicine allows you to get the necessary therapeutic effect, even if the pathology is complicated by the addition of a bacterial infection. An agent containing interferon is used to treat pneumonia, meningitis, sepsis, enterovirus infection and candidiasis.

Viferon 1000000 is prescribed for diseases caused by urogenital infection.

It is included in the treatment regimen for chlamydia, ureaplasmosis, trichomoniasis, bacterial vaginosis, gardnerellosis, mycoplasmosis, cytomegalovirus and papillomavirus infections. The drug helps to cure chronic viral hepatitis (types B, C and D), even if the patient has signs of cirrhosis of the liver.

Viferon helps to achieve a stable remission of chronic glomerulonephritis, which has developed against the background of hepatitis B, herpes virus or cytomegalovirus infection. The drug reduces the risk of developing sexual dysfunction in adult men suffering from prostatitis.

The drug demonstrates high efficiency in the treatment of mild to moderate herpes. It is prescribed for a localized form of the disease (primary or recurrent). Viferon helps to avoid the occurrence postoperative complications purulent character.

Method of application and dosage of Viferon 1000000

Candles Viferon injected into the rectum daily with an interval of 12 hours. The course of therapy depends on the type and severity of the pathology. It is from 5 to 10 days. If necessary, the course of treatment is repeated, making a 5-day break.

During the treatment of recurrent herpesvirus infection, the drug should be taken for at least 10-14 days.

The medicine is prescribed immediately after the first signs of pathology are detected. If plasmapheresis is recommended for a patient suffering from chronic hepatitis, interferon therapy is carried out before the procedure. Candles should be administered daily every 12 hours for 2 weeks.

Since the suppositories contain substances with a low melting point, they quickly become soft in the hands. Therefore, the candle should be used immediately after being removed from the refrigerator. Before the introduction of the drug, you must take a supine position. The candle is inserted to a depth of 5 cm. Due to the small diameter (1 cm) and bullet shape, the suppositories are easily inserted into the rectum without causing discomfort. After the introduction of the candle, you must remain in a supine position for 3-5 minutes. The procedure must be performed with medical gloves.

special instructions

The drug Viferon 1000000 can be used to treat children and pregnant women, since it is an immunomodulatory agent.

During pregnancy

Viferon strengthens immune system which weakens during pregnancy. It reduces the risk of exacerbation of chronic diseases and primary infection. The drug is prescribed to pregnant women if they have urogenital infections of a viral or bacterial nature. Interferon helps to cure cytomegalovirus infection, chlamydia, mycoplasmosis, toxoplasmosis, ureaplasmosis, herpes types 1 and 2.

The drug allows you to restore the microflora of the vagina without the use of eubiotics.

Viferon is prescribed for pregnant women diagnosed with autoimmune diseases. The medicine helps to avoid the use of hormonal drugs used in the treatment of autoimmune pathologies. Interferon alpha reduces the likelihood of a generalized form of intrauterine infection by 5 times.

Viferon 1000000 can be used from the 14th week of pregnancy. The drug is prescribed to women in the II trimester, if they have signs of a recurrent infectious disease. In cases where the pathology poses a danger to the health of a woman, the medicine is used from 12 weeks.

Pregnant women diagnosed with chronic urogenital pathology in remission are recommended to administer the drug vaginally after 28 weeks. Recombinant interferon allows you to completely destroy the colony of pathogens on the surface of the birth canal or dramatically reduce their number. After using the drug, the likelihood of infection of the fetus during passage through the birth canal becomes minimal.

Can children

Viferon 1000000 is used to treat various infectious diseases in children. It allows you to reduce the symptoms of urogenital infections, pyelonephritis and glomerulonephritis, as well as quickly achieve stable remission. The drug is prescribed for acute and chronic forms of the disease. Interferon helps to restore the intestinal microflora in a child.

The dosage of the drug is determined by the doctor individually. It depends on the severity of the pathology and the surface area of ​​the patient's body.

Body surface area is calculated using special formulas that record data on the weight and height of the child. Small children need to insert a candle into the anus shallowly. However, the suppository must be completely immersed in the rectum.

Side effects of Viferon 1000000

Interferon does not cause severe adverse reactions when the recommended doses are observed, since it is applied rectally. Sometimes during treatment, patients experience diarrhea, joint pain and chills. During the use of the drug, patients may complain of depression and loss of strength. Interferon can cause an increase in body temperature. Flu-like symptoms gradually decrease and disappear without treatment. To prevent the occurrence of adverse reactions, patients are prescribed drugs, which include paracetamol.

Contraindications

A contraindication to the use of Viferon 1000000 is the body's sensitivity to the components.

Overdose

A short-term excess of the dosage can lead to an allergic reaction on the skin (redness, rash). With prolonged use of Viferon in high doses, patients may develop signs of a violation of the homeostasis system (thrombocytopenia, anemia, leukopenia, increased levels of alkaline phosphatase). Against the background of long-term use of the drug, fluctuations sometimes occur blood pressure and sleep disorders. Symptoms disappear after the dosage is reduced or the drug is discontinued.

Interoperability and Compatibility

Viferon can be combined with antibiotics, hormonal drugs, chemotherapy drugs, immunosuppressants and interferon inducers. Interferon helps reduce toxic effects on the body medications without diminishing their effectiveness.

With alcohol

Alcohol does not reduce effectiveness medicinal product, however, during the use of alcoholic beverages, the body's immune response weakens. Therefore, to achieve the desired therapeutic effect, it is necessary to increase the dosage of the drug.

Manufacturer

The drug Viferon is manufactured by Feron LLC, created on the basis of the Research Institute of Epidemiology and Microbiology named after A.I. N.F. Gamaleya RAMS.

Terms of dispensing from pharmacies

Viferon 1000000 is sold without a doctor's prescription.

Price

The cost of packaging a medicinal product (10 suppositories) is from 509 to 596 rubles.

Terms and conditions of storage

The medicinal product should be stored in a refrigerator at a temperature of +2 ... + 8 ° C for no longer than 36 months.

Analogues

Analogues of Viferon are: Leukinferon, Nazoferon, Grippferon, Reaferon, Realdiron, Intron-A, Altevir, Vitaferon, Laferobion.

Interferon alpha-2 (Interferon alpha-2)

Latin name of the drug Viferon®

Viferon

ATH:

L03AB01 Interferon alfa

Pharmacological groups

- Antiviral (excluding HIV) agents
- Interferons

Nosological classification (ICD-10)

A41.9 Septicemia, unspecified
A49.3 Mycoplasma infection, unspecified
- A59.0 Urogenital trichomoniasis
A74.9 Chlamydial infection, unspecified
- B00.0 Herpetic eczema
- B00.1 Herpetic vesicular dermatitis
- B18 Chronic viral hepatitis
B25.9 Cytomegalovirus disease, unspecified
- B34 Viral infection of unspecified location
B37.3 Vulvar and vaginal candidiasis (N77.1)
G03.9 Meningitis, unspecified
- J06.9 Acute infection upper respiratory tract, unspecified
- J11 Influenza, virus not identified
- J18 Pneumonia without specification of the causative agent
- N39.0 Infection urinary tract no localization set
- N76 Other inflammatory diseases of the vagina and vulva
O35.3 Fetus affected (suspected) due to maternal viral disease requiring maternal medical attention
O35.8 Other fetal anomalies and lesions (suspected) requiring maternal medical attention

Composition and form of release

Ointment for external and local use 1 g
- interferon human recombinant alpha-2 40000 IU
- tocopherol acetate 0.002 g
- excipients: anhydrous lanolin; medical vaseline; peach oil; purified water
in aluminum tubes of 12 g; in a cardboard box 1 tube.

Gel for topical application 1 ml
- interferon human recombinant alpha-2 36000 IU
- excipients: alpha-tocopherol acetate solution - 5%; methionine alcohol solution - 2%; benzoic acid solution - 0.4%; citric acid
- solution - 10%; sodium tetraborate solution - 3%; sodium chloride solution - 10%; human serum albumin solution - 10%; glycerol
- distilled; sodium carboxymethylcellulose; purified water
- in aluminum tubes of 10 ml; in a pack of cardboard 1 tube

Suppositories for rectal use 1 supp.
- interferon human recombinant alpha-2:
- 150,000 IU
- 500,000 IU
- 1000000 IU
- 3,000,000 IU
- excipients: ascorbic acid - 0.015 g (150,000 IU), 0.022 g (500,000 IU, 1,000,000 IU, 3,000,000 IU); tocopherol acetate - 0.055 g; base - cocoa butter or solid fat
in blisters PVC / PVC, 10 pcs.; in a pack of cardboard 1 pack.

Description of the dosage form

Ointment - yellow or yellowish-white, viscous, homogeneous, with a specific smell of lanolin.

Gel is a homogeneous, opaque, gel-like mass of white color with a grayish tinge.

Suppository - bullet-shaped, yellowish-white color of a homogeneous consistency. Color heterogeneity in the form of marbling and the presence of a funnel-shaped depression on the cut is allowed. The diameter of the suppository is not more than 10 mm.

pharmachologic effect

Pharmacological action - immunomodulatory, antiviral.

Clinical pharmacology

Biological properties: Interferon human recombinant alpha-2 has pronounced antiviral, immunomodulatory and antiproliferative properties.
The complex composition of preparations (ointments, suppositories, gels) causes a number of new additional effects: in the presence of antioxidants (tocopherol acetate and / or ascorbic acid, benzoic or citric acids, as well as methionine), the specific antiviral activity of human recombinant interferon alpha-2 increases, its immunomodulatory effect on T- and B-lymphocytes, the level of immunoglobulin E normalizes, the functioning of the endogenous interferon system is restored. Alpha-tocopherol acetate, ascorbic acid, benzoic and citric acids, as well as methionine, being highly active antioxidants, have pronounced anti-inflammatory, membrane-stabilizing and regenerating properties.
It has been established that when using the drug Viferon rectal suppositories, there are no side effects that occur with parenteral administration of interferon preparations, and antibodies are not formed that neutralize the antiviral activity of interferon.

Indications for Viferon®

Ointment:
- viral (including herpetic) lesions of the skin and mucous membranes of various localization.

Gel:
- prevention and treatment of children with recurrent stenosing laryngotracheobronchitis and often suffering from acute respiratory diseases;
- treatment of adults with chronic recurrent herpetic infection of various localization.

suppositories
In complex therapy:
- various infectious and inflammatory diseases in children, incl. newborns and premature babies: SARS, influenza, incl. complicated by a bacterial infection, pneumonia (bacterial, viral, chlamydial), meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, CMV infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis);
- chronic viral hepatitis B, C, D in children and adults, incl. in combination with the use of plasmapheresis and hemosorption, chronic viral hepatitis - a pronounced degree of activity and complicated by cirrhosis of the liver;
- adults, incl. pregnant women with urogenital infections (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis), primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate course, incl. h. urogenital localization;
- influenza and other acute respiratory viral infections and acute respiratory infections, incl. complicated by bacterial infection in adults.

Contraindications

Ointment: individual intolerance to the components of the drug.

Gel: individual intolerance to the drug, manifested as a local allergic reaction.

Suppositories: hypersensitivity to any of the components of the drug.

Use during pregnancy and lactation

Ointment: since with external and local application, the systemic absorption of interferon is low and the drug has an effect only in the lesion, it is possible to use the drug Viferon (ointment) during pregnancy and breastfeeding.

Gel: since when applied topically, the systemic absorption of interferon is low and the drug has an effect only in the lesion, it is possible to use the drug Viferon (gel) during pregnancy and breastfeeding. During lactation, do not use the drug on the breast and nipple area due to the ability of the drug to form a long-lasting film on the skin surface.

Suppositories: the drug is approved for use from the 14th week of pregnancy. It has no restrictions for use during lactation.

Side effects of the drug Viferon®

Ointment: not marked.

Gel: in exceptionally rare cases, some highly sensitive individuals may experience a local allergic reaction. In such cases, the use of the drug is stopped.

Suppositories: in rare cases - allergic reactions(skin rash, itching). These phenomena are reversible and disappear 72 hours after discontinuation of the drug.

Interaction

Viferon preparations (ointment, gel and suppositories) are compatible and well combined with all drugs used in the treatment of viral and other diseases (antibiotics, chemotherapy drugs, corticosteroids).

Dosage and administration

Ointment, externally and locally.

Apply a thin layer on the lesions 3-4 times a day and rub gently. Duration of treatment - 5-7 days. It is recommended to start treatment at the first signs of lesions of the skin and mucous membranes (itching, burning, redness). In the treatment of recurrent herpes, it is desirable to start treatment in the prodromal period or at the very beginning of the appearance of signs of relapse.

Gel locally.

In order to prevent acute respiratory infections and recurrent stenosing laryngotracheobronchitis, children are applied with a hard swab to the surface of the tonsils 3 times a day for 3 weeks, 2 times a year; with therapeutic purpose the drug is prescribed 5 times a day in the acute period of the disease (5-7 days), then 3 times a day for the next 3 weeks.

In the treatment of adults with chronic recurrent herpetic infection of various localization, treatment is started as soon as possible from the onset of relapse, preferably during the period of precursors. The drug is applied to the affected surface 3 to 7 times a day for 3-5 days. If necessary, the duration of the course is increased to 10 days. Quantity repeated courses not limited. The use of the gel is permissible against the background of therapy with other drugs. When applying the gel to the affected area in 30-40 minutes, a thin film is formed, on which subsequent applications are made. If desired, the film can be peeled off or washed off with water.

When applying the gel to the affected mucous surface, it is preliminarily dried with a gauze swab.

Suppositories, rectally.

In the complex therapy of various infectious and inflammatory diseases in newborns, incl. premature: newborns, incl. premature babies with a gestational age of more than 34 weeks - Viferon 150,000 IU daily, 1 supp. 2 times a day after 12 hours. The course of treatment is 5 days. Premature newborns with a gestational age of less than 34 weeks - Viferon 150,000 IU daily, 1 supp. 3 times a day after 8 hours. The course of treatment is 5 days.

The recommended number of courses for various infectious and inflammatory diseases in children, incl. newborns and premature babies: influenza, SARS, incl. complicated by a bacterial infection - 1-2 courses; pneumonia (bacterial, viral, chlamydial) - 1-2 courses; sepsis - 2-3 courses, meningitis - 1-2 courses, herpes infection - 2 courses, enterovirus infection - 1-2 courses, CMV infection - 2-3 courses, mycoplasmosis, candidiasis, incl. visceral, - 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy with Viferon rectal suppositories can be continued.

In the complex therapy of chronic viral hepatitis B, C, D in children and adults

For children with chronic viral hepatitis, the drug is prescribed in the following age dosages: up to 6 months - 300,000-500,000 IU / day; from 6 to 12 months - 500,000 IU / day. At the age of 1 to 7 years - 3,000,000 IU / m2 / day; children over 7 years old - 5,000,000 IU / m2 / day. The calculation of the dose of the drug for each individual patient is made by multiplying the recommended dosage for a given age by the body surface area calculated from the nomogram to calculate the body surface area by height and weight according to Harford, Terry and Rourke. Divided into 2 injections, rounded up to the dosage of the corresponding suppository. The drug is used 2 times a day after 12 hours for the first 10 days daily, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory parameters.

Children with chronic viral hepatitis of a pronounced degree of activity and cirrhosis of the liver before plasmapheresis and / or hemosorption are shown to use the drug for 14 days daily, 1 supp. 2 times a day after 12 hours (children under 7 years old - Viferon 150,000 IU; children over 7 years old - Viferon 500,000 IU).

Adults with chronic viral hepatitis - Viferon 3,000,000 IU, 1 supp. 2 times a day after 12 hours for 10 days daily, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory parameters.

In complex therapy in adults, incl. pregnant women with urogenital infections (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis, primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate course, incl. urogenital localization)

Adults, with the above infections, except for herpetic - Viferon 500,000 IU, 1 supp. 2 times a day after 12 hours Course - 5-10 days. According to clinical indications, therapy can be continued, the interval between courses is 5 days.

With herpetic infection - Viferon 1,000,000 IU, 1 supp. 2 times a day after 12 hours. The course of treatment - 10 days or more - with recurrent infection. It is recommended to start treatment immediately when the first signs of damage to the skin and mucous membranes appear (itching, redness, burning). In the treatment of recurrent herpes, it is desirable to start treatment in the prodromal period or at the very beginning of the manifestation of signs of relapse.

In pregnant women with urogenital infection, including herpetic, in the II trimester of pregnancy (starting from 14 weeks) - Viferon 500,000 IU, 1 supp. 2 times a day after 12 hours for 10 days, then 1 supp. 2 times a day after 12 hours for 5 days. The prophylactic course is repeated every 4 weeks. If necessary, it is possible to conduct a treatment course before childbirth.

In the complex therapy of influenza and other acute respiratory viral infections and acute respiratory infections, incl. complicated by a bacterial infection in adults: Viferon 500,000 IU, 1 supp. 2 times a day every 12 hours daily. The course of treatment is 5-10 days.

special instructions

Ointment. Store the opened package in the refrigerator for no more than 14 days.

Gel. Store the opened package in the refrigerator for no more than 10 days.

There are no age restrictions for the use of the gel.

Shelf life of the drug Viferon®

2 years.

Storage conditions of the drug Viferon®

In a dry, dark place, at a temperature of 2-8 °C.
Faina 2018-11-12 19:17:24

Hello! Can you please tell me if viferon suppositories for papillomavirus are vaginal or rectal? Confused, thanks

Menshchikova Galina Vladimirovna Dermatovenereologist, dermatooncologist. Candidate of Medical Sciences. Doctor of the first category. Over 15 years experience:

Good afternoon. Rectal

Elena 2018-06-12 10:13:11

If candles are two days without a refrigerator, can they be used?

During seasonal temperature fluctuations colds are normal. First of all, children with unformed immunity suffer. Numerous help put the baby on his feet. There are also medicines. complex action, which not only perfectly remove the symptoms of the disease, but also reduce the temperature, improve general state sick. The drug "Viferon" (candles 150,000 IU) is popular. This tool quickly restores the health of a child of any age. But before use, you should consult with a pediatrician, and also carefully study the instructions.

Packaging, composition and form of release

Candles "Viferon" - this is with an antiviral effect. You can apply it from early age. The main active ingredient is interferon. The medicine is produced in the form of a bullet-shaped form of a light shade. The drug may have an uneven color and a recess in the longitudinal section. The diameter of the suppositories is about 10 mm.

As excipients in the preparation are used: α-tocopherol acetate, polysorbate, cocoa butter and confectionery fat, disodium edetate dihydrate, benzocaine, and ascorbic acid. These elements are absolutely safe for newborn babies. Some adults may develop hypersensitivity.

The drug may have a different dosage of the active substance. "Viferon 1 150000ME N10" (candles) for preschool children are most often used. Adults are offered a medicine in an increased dosage. In pharmacies, candles are dispensed without a prescription. You can buy a pack of medicines of 10 candles. Also on sale you can find gel and ointment "Viferon". But it is candles that are more often used for babies. infancy.

pharmachologic effect

"Viferon" is a combination drug, the effect on the body of which is due to the main active elements that make up its composition. The drug has a systemic immunomodulatory effect. Thanks to this, the patient quickly regains strength after an infectious disease that is viral or bacterial in nature.

Interferon has a negative effect on viruses and microbes. If a bacterial infection has joined the disease, treatment should be continued with the use of antibiotics. Candles "Viferon" can only be used as an aid.

Benzoin, which is part of the drug "Viferon", plays the role of a local antiseptic. It is this component that can reduce the permeability of cell membranes for sodium ions. Due to this, the likelihood of developing pain impulses is significantly reduced. In addition, benzocaine contributes to the speedy regeneration of tissues and the restoration of the patient's normal state of health.

Indications

Gel, ointment and suppositories "Viferon" have an excellent anti-inflammatory effect. Instructions for use states that the drug can be used in combination with other medicines in the treatment of infectious and inflammatory diseases in preschool and infant children (including newborns and premature babies). Candles can also be used to treat ailments that are bacterial in nature. Candles "Viferon" can be prescribed for diseases such as pneumonia, influenza, SARS, meningitis, intrauterine infection, sepsis, mycoplasmosis, candidiasis.

The drug is prescribed for adults and children as part of complex therapy. various forms hepatitis. Candles quickly restore the normal state of the patient's body and help fight infection. Additionally, a specialist may prescribe plasmapheresis and hemosorption. The drug can also be used if the disease is complicated by cirrhosis of the liver.

Adults with a urogenital infection may also be prescribed a drug in the form of an ointment or suppository. The drug "Viferon" can be used to treat pregnant women. The composition of the drug is absolutely safe and does not affect the normal. The drug is prescribed for diseases such as cytomegalovirus infection, chlamydia, vaginal candidiasis, microplasmosis, herpetic infection of the skin and mucous membranes.

The instruction "Viferon" (for children) reports that the drug is not used as monotherapy. The medicine has only an auxiliary effect in the treatment of infectious diseases. Additionally, the specialist must prescribe drugs in accordance with the form of the disease, as well as the individual characteristics of the patient's body.

Contraindications

The drug is absolutely safe. It is no coincidence that it is used to treat newborn babies and pregnant women. In some cases, hypersensitivity to the components of the drug can only develop. It manifests itself in the form of an allergic reaction. The patient may develop hives or a rash on the skin. This condition is most often accompanied by itching. Allergies do not require special treatment, and unpleasant symptoms disappear within 72 hours after stopping the drug.

In rare cases, patients may experience swelling of the limbs or face. This state requires special attention. Quincke's edema is considered the most dangerous. If the patient's tongue or mucous membrane of the larynx begins to swell, it is necessary to immediately call an ambulance. If hypersensitivity occurs, you should immediately stop using Viferon (suppositories). The instruction informs about the main signs of manifestation of hypersensitivity.

Dosage

The drug is taken only rectally. Candles can only be used as part of the complex therapy of infectious and inflammatory diseases. The drug "Viferon" for children may be prescribed. Instructions, application, dosage - all this can be suggested by the doctor. Newborns or premature babies who were born after 34 weeks of gestation are prescribed the drug at a dosage of 150,000 IU. One suppository is administered daily 2-3 times a day (depending on the severity of the disease). The course of treatment usually lasts a week. If the child is recovering quickly, the administration of the drug can be stopped already on the fifth day.

For premature babies who were born before 34 weeks of gestation, the dosage may be reduced. Pediatricians recommend using the drug no more than twice a day. Each time you need to enter only one candle.

Complex diseases complicated by a bacterial infection are treated in several courses. To eliminate the symptoms of pneumonia, for example, the drug is taken for 5 days. Next, you need to take a week break and start the five-day course again. This is due to the immunomodulatory properties of the drug "Viferon". Initially, an interferon-based drug helps fight the disease, and then it helps to restore the body's defenses.

In chronic viral hepatitis, "Viferon" (candles) for children can also be prescribed. Instructions, dosage - all this can be clarified with the pediatrician. The daily rate is set depending on the age of the patient, as well as the individual characteristics of his body. Babies of the first year of life are prescribed no more than 500 thousand IU per day. For children over 7 years of age, the dosage is determined depending on body weight and can be 3 million / m 2 of body surface area. Children over 14 years of age are prescribed 5 million / m 2 of body surface area. The entire daily rate can be divided into 3-4 doses.

Children with chronic hepatitis complicated by liver cirrhosis may also be given an interferon-based drug before plasmapheresis. Reviews of rectal candles "Viferon" 150,000 IU show that babies feel much better after the procedure. It is necessary to take the drug within two weeks before plasmapheresis. Two suppositories are administered daily with an interval of 12 hours.

Overdose and side effects

To date, there are few data on overdose. medicines based on interferon. It can be assumed that the use of the drug in large quantities can lead to an increase in side effects. Most often they manifest themselves in the form of allergic reactions. Patients may experience itching or hives. Less commonly, there is swelling of the extremities, face, oral mucosa.

Babies in the first days of taking the drug can be moody and whiny. But this may be due primarily to the painful condition of the child. Pediatricians do not recommend using any medications for the treatment of children on their own. Worth clarifying all necessary information before taking the drug "Viferon" (instruction, application). Candles, although they are safe, must be taken strictly according to the instructions.

drug interaction

Interferon-based preparations are perfectly combined with medicines that are used to treat infectious and inflammatory diseases. Despite this, the patient should consult a doctor before starting treatment.

People suffering from various chronic diseases requiring constant drug therapy, should clarify with the doctor all the necessary information about "Viferon 1" (candles 150000ME No. 10). The instruction does not describe negative interactions with other medicines. But the patient should consult a doctor in order to avoid the development of side effects.

Are there analogues?

Pediatricians most often prescribe "Viferon" (candles) for children. The instruction "Viferon 150000 IU" states that the drug is completely safe and can be used to treat many infectious diseases that are bacterial in nature. What if the patient has a hypersensitivity, or if the pharmacy does not have the right drug? A specialist will always be able to appoint a high-quality analogue. For the treatment of infectious diseases in babies, Genferon candles are often used. The composition of the drug includes three active ingredients at once. These are interferon, taurine and benzocaine. Additionally, elements such as solid fat, dextran, polyethylene oxide, purified water, lemon acid, sodium citrate, as well as T2 emulsifier.

The drug "Genferon" may well replace the drug "Viferon 150000". The instruction of a candle for children advises using it for the treatment of newborns and premature babies. In adult patients, the drug is used as part of complex therapy for the treatment of such ailments as adnexitis, balanitis, vulvovaginitis, trichomoniasis, mycoplasmosis, viral candidiasis, etc. Candles also have a positive effect on genital herpes.

Candles "Viburkol" - another popular drug with anti-inflammatory action. The drug is used as part of complex therapy in the treatment of bacterial and viral infections for kids. This is a homeopathic remedy. Therefore, there are no contraindications. The drug in rare cases can cause hypersensitivity. Candles "Viburkol" can completely replace the medicine "Viferon 150000". The instructions for a candle for children call it not only an antiviral, but also an antipyretic. The very next day after the start of therapy, the child begins to feel much better.

In this article, you can read the instructions for using the drug Viferon. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Viferon in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Viferon in the presence of existing structural analogues. Use for the treatment of hepatitis, herpes, influenza and other infectious diseases in adults, children, as well as during pregnancy and lactation. Children's forms of the drug and methods of use.

Viferon- a preparation of human recombinant interferon alfa-2. It has pronounced antiviral, antiproliferative and immunomodulatory properties.

The complex composition of the gel and ointment Viferon causes a number of additional effects. In the presence of tocopherol acetate, the specific antiviral activity of interferon alfa-2 increases, its immunomodulatory effect increases (stimulation of the phagocytic function of neutrophils in the lesions). Tocopherol acetate, being a highly active antioxidant, has anti-inflammatory, membrane-stabilizing and regenerating properties.

When applied in the form of a gel, the gel base maintains the prolonged action of the drug, and the excipients support the stability of the specific activity and the proper microbiological purity of the drug.

Pharmacokinetics

With external and local application, systemic absorption of interferon is low.

Indications

For gel:

  • prevention and treatment of children with frequent acute respiratory infections;
  • prevention and treatment of recurrent stenosing laryngotracheobronchitis in children;
  • treatment of chronic recurrent herpetic infection of various localization in women.

For ointment:

  • treatment of viral (including those caused by the herpes virus) infections of the skin and mucous membranes.

Suppositories (candles):

  • various infectious and inflammatory diseases in children, incl. newborns and premature babies: SARS, influenza, incl. complicated by a bacterial infection, pneumonia (bacterial, viral, chlamydial), meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, CMV infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis);
  • chronic viral hepatitis B, C, D in children and adults, incl. in combination with the use of plasmapheresis and hemosorption, chronic viral hepatitis of a pronounced degree of activity and complicated by cirrhosis of the liver;
  • adults, incl. pregnant women with urogenital infections (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis), primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate course, incl. h. urogenital localization;
  • influenza and other acute respiratory viral infections and acute respiratory infections, incl. complicated by bacterial infection in adults.

Release form

Candles (suppositories) 150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU.

Ointment for local and external use.

Gel for topical use.

Instructions for use and dosage

Gel

For the prevention of acute respiratory infections and recurrent stenosing laryngotracheobronchitis in children, the gel is applied with a hard swab to the surface of the tonsils 3 times a day for 3 weeks. After 6 months, a second course is carried out similarly. Prevention of these diseases is recommended 2 times a year in spring and autumn.

For the treatment of acute respiratory infections and recurrent stenosing laryngotracheobronchitis in children, the gel is applied with a hard swab to the surface of the tonsils 5 times a day for 5-7 days, then 3 times a day for 3 weeks.

In chronic recurrent herpes infection of various localization in women, treatment begins as early as possible from the onset of relapse, preferably during the period of precursors. The gel is applied to the affected surface 3 to 7 times a day for 10 days. If necessary, the duration of the course is increased to 10 days. The number of repeated courses is not limited.

When Viferon gel is applied to the affected area, a thin film is formed after 30-40 minutes, on which you can continue to apply the drug. If desired, the film can be peeled off or washed off with water. If it is necessary to apply the gel to the affected surface of the mucous membrane, it should first be dried with a gauze swab.

Ointment

In the treatment of viral (including those caused by the herpes virus) infections of the skin and mucous membranes, the ointment is applied in a thin layer to the lesions 3-4 times a day and gently rubbed in, the duration of treatment is 5-7 days. It is recommended to start treatment immediately when the first signs of skin and mucous membrane lesions (itching, burning, redness) appear. When treating recurrent herpes, it is preferable to start treatment in the prodromal period or at the very beginning of the appearance of signs of relapse.

Candles

As part of the complex therapy of infectious and inflammatory diseases in children

Newborns (including premature babies with a gestational age of more than 34 weeks) are prescribed Viferon 150 thousand IU, 1 suppository 2 times a day with an interval of 12 hours. The course of treatment is 5 days.

Premature newborns with a gestational age of less than 34 weeks are prescribed Viferon 150 thousand IU, 1 suppository 3 times a day with an interval of 8 hours. The course of treatment is 5 days.

The recommended number of Viferon courses for various infectious and inflammatory diseases in children, incl. newborns and premature babies: influenza, SARS, incl. complicated by a bacterial infection - 1-2 courses; pneumonia (bacterial, viral, chlamydial) - 1-2 courses; sepsis - 2-3 courses; meningitis - 1-2 courses; herpetic infection - 2 courses; enterovirus infection - 1-2 courses; cytomegalovirus infection - 2-3 courses; mycoplasmosis, candidiasis, incl. visceral - 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.

As part of the complex therapy of chronic viral hepatitis B, C, D in children and adults

In chronic viral hepatitis in children, the dose of the drug depends on age. For children under the age of 6 months, Viferon is prescribed at a dose of 300-500 thousand IU per day; at the age of 6 to 12 months - 500 thousand IU per day. Children aged 1 to 7 years - 3 million / m2 of body surface area per day, over the age of 7 years - 5 million / m2 per day. The dose of the drug for each individual patient is calculated by multiplying the dose recommended for a given age by the body surface area calculated from the nomogram for calculating the body surface area by height and weight according to Harford, Terry and Rourke is divided into 2 injections, rounded up to the dosage of the appropriate suppository. The drug is used 2 times a day after 12 hours for the first 10 days daily, then 3 times a week every other day for 6-12 months. The duration of the course is determined by clinical efficacy and laboratory parameters.

Children with chronic viral hepatitis of a pronounced degree of activity and liver cirrhosis before plasmapheresis and / or hemosorption are shown to use Viferon 1 suppository 2 times a day with an interval of 12 hours for 14 days (children under the age of 7 years - Viferon 150 thousand IU, children over 7 years old - Viferon 500 thousand IU).

Adults with chronic viral hepatitis are prescribed Viferon 3 million IU, 1 suppository 2 times a day with an interval of 12 hours for 10 days daily, then 3 times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory parameters.

As part of complex therapy in adults, incl. in pregnant women with urogenital infection (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, human papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis), with primary or recurrent herpetic infection of the skin and mucous membranes (localized form, mild and moderate course, including urogenital form)

Adults with the above infections, except for herpes, are prescribed Viferon 500 thousand IU, 1 suppository 2 times a day after 12 hours. The course is 5-10 days. According to clinical indications, therapy with Viferon in the form of rectal suppositories can be continued with an interval between courses of 5 days.

In case of herpetic infection, Viferon is prescribed 1 million IU, 1 suppository 2 times a day after 12 hours. The course of treatment is 10 days or more in case of recurrent infection. It is recommended to start treatment immediately when the first signs of skin and mucous membrane lesions (itching, burning, redness) appear. In the treatment of recurrent herpes, it is desirable to start treatment in the prodromal period or at the very beginning of the manifestation of signs of relapse.

In pregnant women with urogenital infection (including herpetic) in the 2nd trimester of pregnancy (starting from week 14) - Viferon 500 thousand IU 1 suppository 2 times a day with an interval of 12 hours for 10 days, then 1 suppository 2 once a day with an interval of 12 hours 2 times a week - 10 days. Then, after 4 weeks, prophylactic courses of the drug Viferon 150 thousand IU are carried out, 1 suppository every 12 hours for 5 days, the prophylactic course is repeated every 4 weeks. If necessary, it is possible to conduct a treatment course before childbirth.

As part of the complex therapy of influenza and other acute respiratory viral diseases (including those complicated by a bacterial infection) in adults

Apply Viferon 500 thousand IU, 1 suppository 2 times a day with an interval of 12 hours daily. The course of treatment is 5-10 days.

Side effect

  • allergic reactions (skin rashes, itching). For local forms - at the site of application of the ointment or gel.

Contraindications

  • hypersensitivity to the components of the drug.

Use during pregnancy and lactation

The drug is approved for use from the 14th week of pregnancy.

It has no restrictions for use during lactation.

special instructions

Possible allergic reactions are reversible and disappear 72 hours after the end of the drug.

drug interaction

Viferon is compatible and well combined with all drugs used in the treatment of the above diseases (including antibiotics, chemotherapy drugs, corticosteroids).

Analogues of the drug Viferon

Structural analogues according to active substance:

  • Interal-P

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.